Down with the March 15th confusion! Long Live the March 15th confusion!

23. July 2010


Section 9006 of the health care bill -- just a few lines buried in the 2,409-page document -- mandates that beginning in 2012 all companies will have to issue 1099 tax forms not just to contract workers but to any individual or corporation from which they buy more than $600 in goods or services in a tax year.

The stealth change radically alters the nature of 1099s and means businesses will have to issue millions of new tax documents each year.



Health care law's massive, hidden tax change

Is this really the best way to go about job creation? By taxing employers (esp the small biz ones)?

Tech ,



Leave a comment..

Why I love HN

9. July 2010
The process is amazing. It's a giant highly optimized molecular recognition library. Random diversity in antibody binding motifs is generated by guided mutation of the DNA coding for the proteins in the antibody. This wide repertoire is then screened for antibodies that react to 'self' molecular patterns in the body, and the B cells producing those self-reacting antibodies are deleted. One B cell produces only one kind of antibody.

There is also evidence that this antibody repertoire is further primed and refined by constant interaction with the incredible molecular diversity produced from the bacteria that live on our mucosa (that is, barrier interfaces with the environment like the lining of the gut and lungs and the skin).

The immune system naturally tweaks antibodies to make them more efficient at binding (Affinity maturation it's called). If you are trying to make a vaccine, you are better off starting off with an antibody which has already had all the hard work done on it.

It should be pointed out that the donor they used is actually infected with HIV, the antibody didn't protect him because prior to infection it wasn't affinity matured or present in high enough concentration.

If there was a heirarchy of medical treatments, vaccines would surely be at the top. A jab when you are too young to remember and suddenly debilitating fatal diseases that have plagued humans for thousands of years are no longer a problem. The immune system is unique in that you can give information to it, you can communicate with it. It's an information technology, actually. I think this is why vaccines are so fantastic, it is a treatment that collaborates with the body. Pretty much all other medical therapies involved taking a broken system and breaking it even more to achieve some kind of withered stability which is inevitability temporary and has consequences for the organism as a whole (eg giving steroids for rheumatoid arthritis, chemotherapy for cancer). The seasonal flu vaccine is a global immune system in action. It's a molecular rss feed, an app update, a glycoprotein tweet whatever analogy you care to use, perhaps one day an individual's immune system will be part of a greater whole linked via information tech. The immune cloud it might be called.

And millions will still die because of war and poor sanitation and exploitation.


here by Gatsky

It is like picking other people's brains for info you never knew how to ask for.

The entire thread can be found here.

Tech, Bio ,



Leave a comment..

Levy on Zuckerberg

3. July 2010
Totally true. But I'm not saying you have to follow some set of strict rules to be a hacker. Zuckerberg has that hacker DNA. Look at how he grew up, the sorts of hacking he did as a kid. Just like Bill Gates: Gates didn't think that information should be free. But he's a hacker who saw a commercial thing and took advantage of it.



With all respect to Levy, Zuckerberg is not a hacker, just a guy that executed something well.

Steven Levy On Mark Zuckerberg And The Hacker Spirit

Tech



Leave a comment..

Here Boy.. Here Boy...

1. July 2010

Homemade Fusion

23. June 2010
He is the 38th independent amateur physicist in the world to achieve nuclear fusion from a homemade reactor, according to community site Fusor.net. Others on the list include a 15-year-old from Michigan and a doctoral student in Ohio.



Scientists say devices like Mr Suppes' pose no real threat to neighbouring communities or the environment because they contain no nuclear materials, such as uranium or plutonium.

"There is no chance of any kind of accident with fusion," says Neil Calder, communications chief for Iter, a multi-national project begun in 1985 with the aim of demonstrating the feasibility of fusion power.

"There's no CO2 pollution, there's no greenhouse gases, you can't use it for proliferation [the spread of nuclear weapons] - it has so many advantages," he said.



Extreme DIY: Building a homemade nuclear reactor in NYC


I will be the first to admit I know absolutely nothing about how this works, but for a layman it sounds mind boggling.

Tech ,



Leave a comment..